Special Issue Title:

Immunotherapy for Gynecological Oncology

Deadline for manuscript submissions: 31 July 2021

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Special Issue Editor

  • Guest Editor

    Tadahiro Shoji, MDE-MailWebsite

    Department of Obstetrics and Gynecology, Iwate Medical University School of Medicine, Japan

    Interests: Ovarian Cancer

Special Issue Information

Dear Colleagues,

In recent years, immunotherapy has been studied as a promising candidate for being the "fourth pillar" in the treatment of gynecological cancer. Unfortunately, however, no cancer vaccine therapy targeting tumor-specific antigens has yet been approved in any field, including the field of gynecological cancer, and progress in the development of such therapies has been slow. In contrast, recently developed immune checkpoint inhibitors, such as anti-cytotoxic T-lymphocyte antigen 4 antibodies and anti-programmed cell death 1 antibodies, have attracted attention because of their dramatic and long-term antitumor effects and have vitalized the development of cancer immunotherapies.

The response rates to immune checkpoint inhibitors are estimated to be up to 30% for melanoma and approximately 10%–20% for other types of cancer, except for Hodgkin's lymphoma. These drugs are expensive and may cause autoimmune adverse events. Future issues related to immune checkpoint inhibitor therapy include the selection of responders, identification of biomarkers useful for determining the optimal treatment duration and other treatment details in responders, and development of therapies for patients who do not respond to immune checkpoint inhibitors.

At present, in the field of gynecology, studies are being conducted to evaluate combinations of multiple cancer immunotherapies and combinations of cancer immunotherapy with chemotherapy, molecular-targeted drugs, or other treatments. Furthermore, personalized peptide vaccine therapy and personalized T-cell transfer therapy based on tumor-specific mutant antigens have been studied in some cancer types and histological types associated with various gene mutations. Thus, cancer immunotherapy can be regarded as a promising therapy in the field of gynecology.

The aim of this special issue of the Journal is to collect new insights on this fascinating topic.

Prof. Dr. Tadahiro Shoji

Guest Editor


Cancer immunotherapy;Cancer vaccination;Immune checkpoint inhibitor;Ovarian cancer;Cervical cancer;Endometrial cancer

Manuscript Submission Information

Manuscripts should be submitted online by submit system. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Original articles, case reports or comprehensive reviews are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. European Journal of Gynaecological Oncology is an international peer-reviewed open access journal published by MRE Press. Please visit the Instructions for Authors page before submitting a manuscript.The Article Processing Charge (APC) for publication in this open access journal is $1200. We normally offer a discount greater than 30% to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.

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Published Papers (2 papers)

Open Access Special Issue

Treatment strategies for ovarian cancer focusing on prostaglandins

Tatsuhiko Shigeto,Yoshihito Yokoyama

DOI: 10.31083/j.ejgo4205148

(This article belongs to the Special Issue Immunotherapy for Gynecological Oncology)

Abstract ( 759 ) PDF (489.96 kB) ( 114 )

Open Access Special Issue

Characteristics of microsatellite instability-high gynecologic cancer and efficacy of pembrolizumab: a single-institution experience

Tomoko Sakamoto Taniguchi,Shinichi Komiyama,Masaru Nagashima,Mineto Morita

DOI: 10.31083/j.ejgo4204113

(This article belongs to the Special Issue Immunotherapy for Gynecological Oncology)

Abstract ( 1069 ) PDF (587.23 kB) ( 155 )

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