Special Issue Title:

Frontier research of nucleotide-related biomarkers in breast cancer

Deadline for manuscript submissions: 01 February 2023

Print Special Issue Flyer (10)

Special Issue Editor

  • Guest Editor

    Prof. Yingkun XuE-MailWebsite

    The First Affiliated Hospital of Chongqing Medical University, China

    Interests: Breast Cancer; Cancer Biomarkers

  • Guest Editor

    Prof. Guangzhen WuE-MailWebsite

    The First Affiliated Hospital of Dalian Medical University, China

    Interests: Cancer Biology; Gene Therapy

Special Issue Information

Dear Colleagues,

Breast cancer is the most common cancer in women worldwide. Data from the Global Cancer Statistical Report shows that in 2020, breast cancer in women surpassed lung cancer for the first time to become the most common cancer in the world, with an estimated 2,261,419 new cases. At the same time, breast cancer is the fifth leading cause of cancer death globally, with 684,996 deaths. In recent years, the incidence and mortality of female breast cancer have risen sharply worldwide, and the burden of the disease has also increased, which has become a major global public health problem.

Nucleotides are the main building blocks of genetic material and are made up of purines (adenine and guanine) and pyrimidines (thymine, uracil, and cytosine). They are essential substances in DNA and RNA biosynthesis, cell signaling, enzymatic regulation and metabolism. Nucleotide metabolism in cancer cells is significantly higher than in normal cells, indicating that the replication and transcription of cancer cells' genetic material are enhanced considerably, providing favorable conditions for cancer cell proliferation and metastasis. Nucleotide synthesis ensures timely DNA replication, is essential for cancer cell proliferation, and is one of the critical elements of cancer metabolism. Therefore, nucleotide metabolism is a potential target for cancer therapy. Although many efforts targeting this attractive metabolic pathway have been reported, key enzymes' metabolic and regulatory mechanisms in nucleotide metabolism remain unclear. Exploring the critical molecules of nucleotides and the biological functions of nucleotide metabolism are expected to greatly improve cancer's clinical diagnosis and targeted therapy.

This special issue aims to organize original research and review articles exploring those promising nucleotide molecules and nucleotide metabolism-related anticancer targets, which may assist in the diagnosis and treatment of cancer, especially breast cancer, including experimental techniques and methods, as well as clinical validation and application.

Prof. Yingkun Xu and Prof. Guangzhen Wu

Guest Editors


Breast Cancer; Nucleotides; Nucleotide Metabolism; Precision Medicine; Gene Therapy

Manuscript Submission Information

Manuscripts should be submitted online by submit system. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Original articles, case reports or comprehensive reviews are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. European Journal of Gynaecological Oncology is an international peer-reviewed open access journal published by MRE Press. Please visit the Instructions for Authors page before submitting a manuscript.The Article Processing Charge (APC) for publication in this open access journal is $1200. We normally offer a discount greater than 30% to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.

Share This Special Issue

Plan Papers (0 papers)

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time