Contemporary surgical management of cervical cancer: minimally invasive surgery, de-escalation and personalized approaches

Dear Colleagues,

Cervical cancer is one of the most common gynaecologic malignancies worldwide despite the implementation of screening programs and HPV vaccination. In recent years, the surgical management of cervical cancer has undergone profound changes driven by advances in imaging, molecular characterization, surgical technology, and a growing emphasis on individualized treatment strategies. The publication of landmark studies has challenged traditional paradigms, particularly regarding the role of minimally invasive surgery, while increasing evidence supports the concept of tailoring surgical radicality according to tumour characteristics and patient-specific factors.

This Special Issue aims to provide a comprehensive overview of contemporary surgical approaches to cervical cancer, covering the entire spectrum of disease management from fertility-sparing procedures to radical surgery and emerging de-escalation strategies. Particular attention will be devoted to the evolving role of minimally invasive surgery, including conventional laparoscopy and robotic-assisted techniques, and to the ongoing efforts to optimize oncologic outcomes while minimizing treatment-related morbidity.

The issue will also explore the growing interest in personalized surgical treatment, incorporating advances in preoperative imaging, sentinel lymph node mapping, molecular profiling, and risk stratification models. Novel approaches aimed at reducing the extent of surgery in carefully selected patients, including less radical procedures for low-risk early-stage disease, will be critically evaluated in light of recent evidence.

Furthermore, contributions addressing fertility preservation, quality of life, functional outcomes, and survivorship will be encouraged, recognizing the increasing importance of patient-centred care in gynaecologic oncology. Reviews and original research focusing on surgical innovations, artificial intelligence, image-guided surgery, enhanced recovery pathways, and multidisciplinary management are also welcome.

By bringing together leading experts in gynaecologic oncology, this Special Issue seeks to provide clinicians, researchers, and surgeons with an up-to-date overview of current evidence and future directions in cervical cancer surgery. The goal is to foster discussion on how surgical treatment can be increasingly individualized, balancing oncologic safety with preservation of function, fertility, and quality of life.